Protein Molecular Weight Markers
Abcam O-Propargylpuromycin, protein marker for imaging.
O-Propargylpuromycin, protein marker for imaging.
The product is subject to the following: Abcam Restricted Use Statement
Abcam 5-Aminofluorescein (Fluoresceinamine, isomer I), Fluorescence marker, 10G
MW 347.3 Da, Purity >95%. Fluorescence marker. Selectively targets malignant glioma tissue in vivo when covalently linked to human serum albumin at a molar ratio of 1:1without bleaching nor penetrating into surrounding brain edema or necrotic tissue. Blood-brain barrier permeable.
The product is subject to the following: Abcam Restricted Use Statement
Cayman Chemical PI-103hydrochlorIde 10mg
A selective FLT3 inhibitor (Kd 1 6 nM) that inhibits the proliferation of MV4-11 cells both in vitro (IC50 0 56 nM) and in in vivo mouse models of FLT3-ITD acute myeloid leukemia
Cayman Chemical CYP1Acod Monclonal ntIbo 500uL
An inhibitor of H-PGDS (IC50 32 nM for the human enzyme) selective for H-PGDS over L-PGDS mPGES-1 COX-1 COX-2 and 5-LO (IC50s 10000 nM for all) inhibits PGD2 production in vivo in rat spleen at 1 mg/kg or 10 mg/kg completely inhibits allergen-induced airway hyperresponsiveness in an ovine model of asthma
Cayman Chemical VItelogenInsturgeon Monc 500uL
An allosteric inhibitor of Bcr-Abl (IC50 0.121 UM) inhibits the Bcr-Abl mutants Bcr-AblG250E Bcr-AblE255V and Bcr-AblM351T (IC50s 4.52 0.38 and 0.93 UM respectively) reduces viral titers in IBV-infected Vero cells at 10 UM increases survival in a recalcitrant mutant Bcr-AblT315I mouse bone marrow transplantation model at 75 mg/kg
Cayman Chemical VItelogenInsalmon Monclo 500uL
A selective brain-penetrable LRRK2 inhibitor (Kis 2 and 18.7 nM in biochemical and cell-based assays respectively) inhibits LRRK2 Ser1292 autophosphorylation in BAC transgenic mice expressing human LRRK2 protein with the G2019S Parkinsons disease mutation (IC50 20 nM in vivo)
